Sigilon Therapeutics is seeking a Scientist to join the Assays group, which develops and performs biological assays for multiple therapeutic programs across the company. 

 

Responsibilities

  • Independently develop and perform standardize protocols for quantifying and assessing the activity of therapeutic proteins, including ELISA / MSD, cell-based assays, and biochemical / enzymatic assays. 
  • Assess scientific literature in a variety of therapeutic areas to design experiments and develop / optimize assays. 
  • Analyze, interpret, and present experimental data in multidisciplinary team meetings. 
  • Write and review SOPs, study reports, posters / publications, and technical sections of regulatory filings. 
  • Coordinate with molecular / cell biology, engineering, and in vivo team members to ensure timely delivery of assay data. 
  • Manage projects with external labs and assay transfers. 
  • Review internally / externally-generated analytical data for accuracy. 
  • Maintain detailed records in electronic lab notebook and sample management system. 
  • Evaluate and facilitate adoption of new technology / equipment to expand the capabilities of the Assays group.

 

Requirements

  • Ph.D. in biochemistry, cell biology, molecular biology, or related discipline. 
  • At least 2 years of experience in the pharmaceutical / biotechnology industry, specifically in developing bioassay protocols. 
  • Experience with cell and molecular biology techniques, including ELISA / MSD, Western blot, mammalian cell culture, and other gene / protein expression assays. 
  • Experience with plate-based readers and analysis software, such as SoftMax Pro, BioTek Gen5, GraphPad Prism, and Excel. 
  • Exceptional attention to detail, particularly as it relates to the accuracy and precision of assays. 
  • Experience with assay qualification and validation in a GLP environment is a plus. 
  • Ability to work effectively with minimal supervision after initial training. 
  • Ability to set priorities and multi-task activities to effectively manage workflows and deliverables. 
  • Strong team orientation, with excellent written and oral communication skills.  

Apply here